Properties of a Penicillin Inactivator Extracted from Penicillin-resistant Staphylococci.
نویسنده
چکیده
منابع مشابه
A study of coagulase-negative staphylococci (CoNS) isolated from bovine mastitis for the presence of penicillin and methicillin resistance-encoding genes in the north west of Iran
Coagulase-negative staphylococci (CoNS) are often associated with bovine mastitis and may be resistant to antimicrobial therapy. The aim of the current study was to investigate the presence of blaZ (responsible for penicillin resistance) and mecA (responsible for methicillin resistance) genes among 108 CoNS belonging to 9 different species isolated from bovine mastitis in seven dairy herds (H1-...
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The use of the quantitative nasal culture was investigated as a means of evaluation of new antimicrobial drugs in man. Cyclacillin was somewhat more active in vitro than penicillin G against penicillin G-resistant organisms. Cyclacillin was highly effective in suppressing staphylococci susceptible to penicillin G in nasal carriers but did not suppress staphylococci resistant to penicillin G. Al...
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Gale and his group have shown that (1) staphylococci grown "deficient" in glutamic acid can concentrate the free amino acid inside the cells, provided a source of eneigy is present (Gale, 1947; Taylor, 1947); (2) penicillin, in growthinhibitory amounts, prevents the uptake of glutamic acid by staphylococci if the organisms are first grown for a short period in the presence of the antibiotic (Ga...
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Staphylococci isolated from 98 mastitic cow’s milk samples were analyzed for the production of alpha,beta and delta-hemolysin on sheep, bovine and horse red blood cells and in vitro susceptibility to several antimicrobial agents. Out of a total of 18 isolated strains, 100% demonstrated hemolytic activity either alone or in combined forms. Among 8 isolates of S. aureus 3 isolates produced α/β an...
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There are a number of reports that bacteria which have been made resistant to antibiotics may be rendered normally susceptible by contact with sensitive organisms, with extracts of such organisms, or with culture filtrates. Some of these reports are mutually contradictory in important respects, and the results have not been reproducible regularly by other workers. Voureka (1948) found that when...
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عنوان ژورنال:
- The Journal of clinical investigation
دوره 24 2 شماره
صفحات -
تاریخ انتشار 1945